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British Journal of Anaesthesia
BJA

Anaphylaxis to the first COVID-19 vaccine: is polyethylene glycol (PEG) the culprit?

Published:December 17, 2020DOI:https://doi.org/10.1016/j.bja.2020.12.020
      Editor—The day after the world watched the first person receiving the coronavirus disease 2019 (COVID-19) vaccine on December 8, 2020, reports of three cases of suspected allergic reactions in connection with the vaccine emerged from the UK. Two were reports of anaphylaxis in healthcare workers, with onset within minutes of vaccination, responding well to treatment with epinephrine. Both recovered fully and were reported to have severe allergies to foods and drugs, respectively. The third case was less severe and did not require epinephrine.

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